Ozempic 0.25/0.5mg pen

What is Ozempic?

Ozempic is the brand name for semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist developed by Novo Nordisk. It belongs to a class of medications called incretin mimetics, which work by:

• Stimulating insulin secretion from pancreatic beta cells

• Suppressing glucagon release (which lowers blood sugar)

• Slowing gastric emptying (leading to prolonged satiety)

• Reducing appetite through direct action on brain receptors

FDA-Approved Uses

1. Type 2 Diabetes Management (Primary Indication):

   • Improves glycemic control in adults

   • Reduces HbA1c by 1.0-1.8%

   • Lowers risk of major cardiovascular events

2. Off-Label Uses:

   • Chronic weight management (higher doses under brand Wegovy)

   • PCOS-related insulin resistance

   • Non-alcoholic steatohepatitis (NASH) research

Dosage Forms & Strengths

• Prefilled Multi-Dose Pens:

  • 0.25 mg/0.5 mg dose pen (starter dose)

  • 1 mg dose pen

  • 2 mg dose pen (newest FDA-approved higher dose)

• Administration:

  • Subcutaneous injection (abdomen, thigh, or upper arm)

  • Once weekly (any time of day, with/without meals)

• Stimulating insulin secretion from pancreatic beta cells

• Suppressing glucagon release (which lowers blood sugar)

• Slowing gastric emptying (leading to prolonged satiety)

• Reducing appetite through direct action on brain receptors

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